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KMID : 0356919940270101474
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Korean Journal of Anesthesiology
1994 Volume.27 No. 10 p.1474 ~ p.1480
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Anaphylactoid Reaction to Atracurium
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백희정
장혜진/김규삼/조상헌/민경업/김유영
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Abstract
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A case is reported of anaphylactoid reaction to atracurium, used for the induction of anesthesia for skin graft in a 36-year-old man. The patient had no previous history of any allergic tendency.
It is not possible to distinguish between direct pharmacological effects and immune-mediated hypersensitivity reactions by clinical observation alone. The mechanism of reaction in this patient was investigated by the leukocyte histamine release
test,
intradermal test, direct intravenous challenge with other induction agents used during the induction of anesthesia and radioallergosorbent test.
The histamine-releasing property of atiacurium, the distinguishing methods between anaphylactic and anaphylatoid reaction, and the anesthetic management for this kind of reaction are discussed.
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KEYWORD
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